Crispr Cas9 Delivery

Comparing Advanced CRISPR-Cas9 Delivery Systems: Specificity, Immunogenicity, and Clinical Progress

The effectiveness and safety of CRISPR-Cas9 gene editing therapies depend critically on delivery systems. This article compares viral vectors like AAVs and lentiviruses, non-viral options like LNPs, and ex vivo methods like electroporation, evaluating their specificity, immunogenicity, and clinical progress.