Gene Editing
5 articles
CRISPR, ZFNs, and TALENs: A Guide to Choosing the Right Gene Editing Tool
This article compares CRISPR-Cas9, ZFNs, and TALENs, detailing their distinct targeting mechanisms and trade-offs between ease of use and precision. It guides researchers in selecting the optimal gene editing tool based on specific scientific goals and required accuracy.
CRISPR yields climate-resilient crops, boosting food security
In 2021, Japan quietly introduced the world's first CRISPR-edited tomato, the Sicilian Rouge High GABA, engineered not just for resilience but enhanced nutritional content.
What is CRISPR Gene Editing and Why is it Revolutionizing Medicine?
In February 2025, KJ Muldoon became the first person to receive a personalized CRISPR therapy for a life-threatening metabolic disorder, according to Nature .
How CRISPR-Cas9 Gene Editing Works: Target, Cut, Repair
CRISPR-Cas9 gene editing works by using a guide RNA to target a specific DNA sequence, a Cas9 enzyme to cut it, and the cell's natural repair mechanisms to alter the gene. This revolutionary technology is being applied to treat genetic diseases and improve crops, but faces challenges in delivery, precision, and ethical considerations, particularly regarding heritable germline edits.
How CRISPR Gene Editing Works to Treat Genetic Diseases
CRISPR-Cas9 gene editing technology, functioning as precise molecular scissors, offers a revolutionary approach to treating genetic diseases by modifying DNA. Its recent FDA approval for sickle cell disease marks a significant milestone, with ongoing research exploring broader applications and addressing challenges in delivery and safety.