Prime Editing

Base Editing vs. Prime Editing: How CRISPR Learned to Rewrite DNA Without Cutting It

Base editing and prime editing are advanced CRISPR technologies that rewrite DNA without making double-strand breaks, offering safer and more precise genetic modifications than traditional CRISPR-Cas9. While base editing excels at specific single-base changes, prime editing provides a broader 'search-and-replace' capability for various edits including small insertions and deletions.