Biotech & Health
Reporting on the convergence of biology and technology, from CRISPR gene editing to the science of longevity.
How CRISPR-Cas9 Gene Editing Works: Target, Cut, Repair
CRISPR-Cas9 gene editing works by using a guide RNA to target a specific DNA sequence, a Cas9 enzyme to cut it, and the cell's natural repair mechanisms to alter the gene. This revolutionary technology is being applied to treat genetic diseases and improve crops, but faces challenges in delivery, precision, and ethical considerations, particularly regarding heritable germline edits.
How AI is Reshaping Every Stage of Drug Development
Artificial intelligence is fundamentally altering the drug development lifecycle, from initial target identification to post-market safety monitoring. While promising accelerated timelines and improved precision, significant challenges in data quality, transparency, and regulatory oversight must be addressed.